{"id":196377,"date":"2025-10-16T12:07:42","date_gmt":"2025-10-16T08:07:42","guid":{"rendered":"https:\/\/abcmedia.am\/?p=196377"},"modified":"2025-10-16T12:39:59","modified_gmt":"2025-10-16T08:39:59","slug":"american-and-british-doctors-manage-to-cure-rare-and-deadly-disease-of-immune-system-in-children","status":"publish","type":"post","link":"https:\/\/abcmedia.am\/en\/news\/196377\/","title":{"rendered":"American and British doctors manage to cure rare and deadly disease of immune system in children"},"content":{"rendered":"\n

An experimental gene therapy developed jointly by American and British scientists has successfully treated dozens of children with a rare and fatal immune disorder, Euronews<\/a> writes.<\/p>\n

The study included 62 children with adenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID) – a disorder caused by genetic mutations that leave children without working immune systems, making them extremely vulnerable to infections.<\/p>\n

Existing therapies for ADA-SCID are expensive and risky, but without treatment it is often fatal within the first two years of life.<\/p>\n

The new treatment involves collecting a child’s blood stem cells – which create immune cells – and inserting a virus that delivers a healthy copy of the ADA gene. The corrected cells are then infused back into the patient, allowing them to produce healthy immune cells.<\/p>\n

After the procedure, it takes six to 12 months for the immune system to reach normal levels, the researchers said.<\/p>\n

Fifty-nine patients were successfully treated with the gene therapy between 2012 and 2019. Since then, their immune functions have remained stable and they have not reported serious complications.<\/p>\n

Five of the children are still healthy more than a decade later.<\/p>\n

The researchers said the study is the largest and longest follow-up of a gene therapy of this kind.<\/p>\n<\/body><\/html>\n","protected":false},"excerpt":{"rendered":"